Handgun Calibers Comparison: From Smallest to Largest [2018]

“Caliber” is a word people often use and misuse when talking about guns.

I was at the range earlier this week and two of my best buds were arguing over which is the better caliber: the 45 or the 40To me it was just another never-ending debate, but it was the number of times both of them said “caliber” that I found amusing — and mildly irritating as well.

Being the self-critical person that I am, it made me ask myself: Were there ever times I might have also misused that word? And are there things about it I might not be aware of?

If you’re like me and you’re asking yourself the same questions, or if you’re new to firearms and you just want to expand your knowledge about handgun calibers in general, read on.


What is a caliber?

The Cambridge Dictionary defines “caliber” as either “the quality of someone or something, especially someone’s ability,” or “the width of the inside of a pipe, especially of the long cylinder-shaped part of a gun, or the width of a bullet”.

I can agree with the first definition, but being a firearms enthusiast, I think the second one has some inaccuracies.

Where it says “the long cylinder-shaped part of a gun”, I think we can all pretty much agree that it’s a gun’s barrel they were referring to, specifically the measurement of the bore.

Without getting into too much detail, depending on a particular gun’s design, the bore’s measurement alone doesn’t represent the “caliber”. Think semi-auto handguns, rifles and shotguns. The chamber and the barrel of any of these guns are formed from the same piece of steel, but the chamber has a different measurement compared to that of the bore.

Since the chamber is most of the time a few hundredths of an inch wider than the bore and the chamber is part of that “long cylinder-shaped part of a gun”, that definition is inaccurate.

Where it says “the width of a bullet”, I think we can all pretty much agree again that it’s a bullet’s cylindrical portion the dictionary was referring to — but it didn’t make a clear distinction as to which portion of the bullet the “caliber” is a measure of.

The portion of the bullet that makes contact with the rifling grooves inside a barrel’s bore as it is propelled by burning gunpowder is, indeed, measured in inches or millimeters and is commonly referred to as “caliber”. But what of the bullet’s nose? Isn’t that also part of the caliber?

Nope. A bullet’s nose is called its “ogive, and it is measured a different way (but we’ll not get into that). So again, The Cambridge Dictionary is inaccurate.

Before I got really into handguns, I remember some of the questions I would often ask myself:

  • Does a 38 beat a 9 because the number 38 is bigger than the number 9?
  • Is the 357 more powerful than any other handgun caliber because it has three digits while most others only have two?
  • If the 357 is more powerful than a 45, is it also more powerful than a 44?
  • Why does the 44 have a Special and a Magnum when the 357 only has a Magnum and no Special?
  • What’s with all the different suffixes after the numbers? What’s an ACP? What’s a WinMag? What’s a Super? What’s a Magnum? And why do some people call the 40 “short and weak” when they’re aware the S&W next to it means Smith and Wesson?

I admit, I used to be that dumb.


Handgun Calibers Comparison

To me, the word “caliber” as it pertains to firearms is a label — not just a measurement of a bullet or a bore’s dimensions — but a way to identify the intrinsic qualities of a cartridge that makes it unique.

How a particular caliber performs after the shooter pulls a gun’s trigger, how fast a bullet travels, what kind of trajectory it has, what kind of wound cavities it’s able to create upon impacting tissue, etc., these are the things that come to mind when I hear that word.

To flesh out all the details, I created a table that lists all of the most common (and not-so-common) handgun calibers and all pertinent info about them:

It’s by no means a complete list, as I’m only including available info online for a total of 52 different handgun calibers, 23 of which are cartridges for semi-autos, 25 are for revolvers and the remaining two wildcards (not wildcats), namely the .22 LR and .22 WMR, are kind of all over the place because they can be chambered in rifles, revolvers and semi-autos.

Categories

To make the comparisons easier, we’re categorizing handgun calibers based on their launching platforms i.e. semi-auto handguns and revolvers; and on their intended purpose: whether they’re only for plinking, self defense, hunting or combinations thereof.

Sub-Categories

Handgun calibers for hunting will be further divided into three sub-categories: varmint, medium game, and large game.

After every handgun caliber has been placed in its respective category, we’ll compare all of them based on their relative strengths and weaknesses in these three key areas:

  • Bullet velocity (the higher a bullet’s velocity, the flatter its trajectory and the longer its effective range);
  • Muzzle energy (the higher a bullet’s muzzle energy, the more powerful it is);
  • Price (the lower the price, the more popular the handguns and ammo for a particular caliber and the better its availability);

Metrics for Analysis

I was initially going to include other metrics like stopping power (for self defense rounds), one-hit-kill potential (for hunting rounds), accuracy, terminal performance and recoil to compare all listed handgun calibers against each other but decided against it because of the following reasons:

Stopping Power

Stopping power and one-hit-kill potential in my opinion (and lot of other sensible gun nuts’) cannot be quantified for a lot of reasons. These are highly debated issues and can be very large topics in and of themselves so I won’t use these metrics.

Suffice it to say not every target hit by a specific bullet center of mass will react the same way: humans have different stature and varying levels of willpower, and bad guys high on meth, regardless of physiological and psychological limitations, will be even harder to take down.

Game animals on the other hand, well there are just too many species to compare. We will not be covering that topic in this analysis.

Theoretically, anyone can place well-aimed heart and head shots in their target given ample time and practice. Granted it’s easier said than done, but guns don’t shoot without someone pulling the trigger, so it’s only right to put the operator in the equation when determining stopping power, one-hit-kill potential and accuracy.

Accuracy

A bullet is accurate if it can consistently hit a target at point of aim over a given distance assuming the shooter knows what he’s doing.

Sounds pretty straightforward, but accuracy also depends on a lot of other variables outside of the shooter’s marksmanship skills.

Some bullet shapes and designs have a higher ballistic coefficient, making them much more accurate than others. Ballistic coefficient has little to do with just a bullet’s diameter, it’s a function of a bullet’s overall dimensions.

The type of sights on a firearm also have a direct influence on accuracy. Reflex sights and red dot sights are great for faster target acquisition but are expensive. Scopes are real accurate for long range shots but rendered useless for bullets with poor ballistic coefficient.

Almost all handguns and revolvers come with either adjustable or fixed iron sights. Whether or not these sights are zeroed properly will greatly affect accuracy as well.

And lastly, barrel rifling stabilizes a bullet by making it spin as it exits the barrel.

Not to complicate this topic, but there are two types of barrel rifling — lands-and-grooves and polygonal, and the number of rifling grooves (in the case of the former) or rifling surfaces (in the case of the latter) affects how fast a bullet would spin, thereby also affecting accuracy.

Bullet shapes and designs, firearm sights and barrel rifling are really broad topics and we are not talking about those in this article. Ergo accuracy as a metric will not be used.

Terminal Performance

A bullet’s terminal performance is measured by how deep it penetrates a given target and what kind of wound cavities it can create.

Terminal performance is largely determined by two things: muzzle energy (which is a function of bullet weight, powder charge and barrel length) and bullet design (a function of price).

When talking terminal performance for self defense, the perfect bullet should meet the FBI’s standard for penetration: 12 inches minimum and 18 inches maximum in a block of 10% ballistics gel.

A Lehigh Defense Xtreme Penetrator .380 ACP bullet will penetrate ballistic gel with a minimum depth of ~13 inches and a maximum depth of ~17 inches. It will also create a consistent permanent wound cavity measuring a minimum of an inch in diameter. So what’s the kicker?

The .380 ACP is considered a weak round.

Yet with a fluted bullet design it can go toe to toe against its bigger brother, the 9mm (FMJ) and even surpass the .45 ACP (JHP) in terms of penetration and wounding capability. But there’s a catch — these new fluted bullet designs can be really expensive.

Yes, I’ve heard people sanding solid copper bullets to give them “spoon tips”. I don’t like messing with bullets so I have no personal experience with spoon tips. 

I wouldn’t recommend using those (unless they came out of a factory, e.g. the spoon tips for the 7.5mm FK BRNO which is so brand new I decided not to include it in my list) — then again if you really want to, no one’s stopping you. You’ve been warned.

But I digress. As far as terminal performance is concerned, when comparing handgun calibers within the same category, bullet design trumps muzzle energy. And there are simply a lot of popular bullet designs out there which is a topic for another day.

Since this article is about handgun calibers, we will not be talking about bullet designs, which is why we are not using terminal performance as a metric.

Recoil

Recoil depends on a few variables, two of which are outside the scope of this analysis: the weight of the handgun (polymer handguns will have more recoil compared to all-steel semi-autos and revolvers) and the platform design (an all-steel semi-auto will always have less felt recoil compared to an all-steel revolver of the same size by virtue of the recoil spring within its slide assembly).

Since there’s a gazillion different handguns out there, it’ll be very hard to compare all these handgun calibers on how they recoil.

Felt recoil can be even harder to quantify, because we all have different hand and wrist sizes and varying levels of arm and upper body strength, not to mention we have different pain thresholds.

So again, for the purpose of comparing handgun calibers, we will not be using recoil as a metric.

Semi-auto Handgun Calibers

A note on this list.

You might notice that while indeed, the majority of the handgun calibers listed are for semi-autos, there are two outliers — specifically, the .22 LR and the .22 WMR.

As mentioned earlier, both those rounds are actually rifle calibers.

But since there is more than a handful of semi-auto handguns and revolvers chambered for those rounds, we decided to include them in this list.

In general, semi-auto handguns can only use rimless cartridges because rimmed cartridges are difficult to stack in box-type magazines. However, we are aware of obscure designs that allow for certain revolver cartridges to chamber in some semi-auto handguns (e.g. Coonan, LAR Grizzly and Desert Eagle in .357 Magnum and some Wildeys, AutoMags and again the Desert Eagle chambered in .44 Magnum).

To make the comparisons simpler, we decided not to include any revolver cartridges in this list.

Semi-auto Calibers for Plinking

The only thing that should concern anyone when choosing a semi-auto handgun caliber just for plinking is price. The cheaper the ammo, the more bang for your buck (literally).

The graph above shows that the .22 LR is THE MOST affordable plinking round for any semi-auto handgun at $0.09 per round.

It is trailed closely by the 9mm at $0.35, while its bigger rimmed brother the .22 WMR (Winchester Magnum Rimfire — or .22 Magnum) comes in third at double the .22 LR’s price.

Semi-auto Calibers For Self Defense

Now we get into the meat of our semi-auto handgun caliber discussion. Compared to revolvers, semi-autos as a launching platform are almost always going to be the better picks when considering getting concealable firearms for self defense.

Our semi-auto handgun caliber lists a total of 17 different cartridges for just this purpose. That is 17 out of the 52 handgun calibers on our list which comprises the majority of semi-auto cartridges in this analysis.

If you don’t have a semi-auto handgun as a CCW and you’re trying to decide which among the most popular self defense rounds you should choose, always consider price (even if you’re too damn rich) because it affects two things:

  • One, handgun options availability (the more competitive a round commercially, the more handguns are built for it, and the more handguns on the market, the better aftermarket support);
  • Two, how often you’ll get to spend time in the range for practice.

Self Defense Semi-Auto Calibers — Pricing

From the graph above, we can see that the 9mm is the cheapest at $0.15 a pop, followed closely by the .40 S&W at $0.21, the .380 ACP at $0.24, the .45 ACP at $0.25, and the .38 Super at $0.29. This shouldn’t really come as a surprise.

Self Defense Semi-auto Calibers – Muzzle Energy

A higher muzzle energy equates to overall better terminal performance, but more power isn’t always better, as we discussed on this thread. If for nothing else, a bullet with too much muzzle energy will be more difficult to shoot accurately and rapidly.

All the handgun calibers listed on the graph above will be adequate for self defense, we’re only comparing them on their muzzle energies to try and differentiate them from each other.

At $0.15 per round and with good ballistic performance, the 9mm simply stands out. It is closely trailed by the .40 S&W, the .45 ACP and the .38 Super. And we can’t dismiss the merits of the .380 ACP — it deserves some kind of recognition if only for the fact that some of the smallest handguns on the market are chambered for it (if you need more info you can check out this thread).

If you want the latest and quite possibly the greatest for CCW, consider the .22 TCM. It has low recoil, more muzzle energy than a .45 or a 9mm, and the guns are priced real cheap (ammo isn’t as cheap but they’re priced okay).

Semi-auto Calibers For Varmint

Semi-auto Calibers For VarmintWhat’s great for plinking is most of the time also great for hunting varmint.

The graph above shows the two .22 rimfire cartridges edging out their other two competitors when it comes to affordability. But if you’re shooting varmint from a hundred yards away, maybe you’ll need to check the velocity graph below:

Semi-auto Calibers For Varmint - Velocity Chart

The .22 Winchester Magnum Rimfire at $0.20 a pop is the fastest of the four semi-auto handgun varmint calibers. Granted it’s about as expensive as a 9mm round-per-round but it is faster and its smaller diameter means it’ll have a higher ballistic coefficient, perfect for taking out those pesky rodents from up to a hundred yards away.

Semi-auto Calibers For Medium Game

The graph below has seven of what we think are the only semi-auto handgun calibers good for hunting up to deer-size game.

Medium Game Semi-auto Caliber — Pricing

The 10mm is the most affordable semi-auto handgun cartridge for medium game. Again, cheaper ammo means more practice, and more practice means more venison on the table for less. At $0.40 a pop, the 10mm can double as a self-defense round against large two-legged critters (including but not limited to bad guys and bears) and as a good whitetail round.

Medium Game Semi-Auto Calibers — Ballistics

Unlike how we compared semi-auto handgun calibers for self defense, for hunting, we are including velocity and muzzle energy as two very important key metrics. This is because of the longer distances where a hunter must take a shot (as opposed to 5- to 10-yards in typical self defense situations).

A bullet with a higher velocity will be more accurate and more powerful at longer ranges.

The 9×25 Dillon takes the lead in the velocity department (highest orange bar, third from left) when comparing semi-auto handgun calibers intended for hunting medium game, which is not surprising — it’s like the .357 SIG on steroids.

It is closely trailed by the 9×23 Winchester, but if we put price in the equation the more affordable 10mm sitting right smack in the middle of the graph should be fast enough with its average velocity of 1,350 feet per second and will be more than adequate for whitetail with its 728 ft.lbf of muzzle energy. 

As far as muzzle energy, the .40 Super is the top dog, but availability issues have been hounding this cartridge since the company that manufactured it went out of business. If you don’t already have a .40 Super handgun, don’t bother buying one.

The 460 Rowland, another similar powerhouse of a wildcat, is just a hair short of muzzle energy but it’s the most expensive medium game cartridge.

Semi-auto Calibers For Large Game

We only have five semi-auto handgun calibers on our list for hunting large game. The graph below compares them on per-round cost.

Large Game Semi-auto calibers — Pricing

Being the eternal cheapskate that I am, even if the .50 AE costs only $1.50 per round, I wouldn’t buy a Desert Eagle to hunt large game. There are infinitely better hunting rifle options and if I wanted to hunt with a handgun, I’d really just opt for a big-bore revolver.

Still, if money isn’t an issue and you’re considering buying (or if you just happen to own) a Desert Eagle chambered in .50 AE, you’d be pleased to know that its 50-caliber round is the most affordable semi-auto handgun caliber for hunting large game.

All the other calibers on the graph above are close to obsolescence if they’re not already obsolete — except maybe for the .44 AMP (Automag Pistol).

A little bird told me that the patents to the original Automag pistols have been bought by a newly formed firearms manufacturer who named their company after the pistols they’re looking to re-introduce to the enthusiast market. If the newer Automag pistols turn out to be cheaper than Deagles I’d gladly get one for bear.

Large Game Semi-Auto Calibers — Ballistics

The .440 Cor-Bon dwarfs all the other big-bore semi-auto handgun calibers on this list when it comes to sheer power and speed. Again, not surprising considering how and why the round was developed.

Like all necked-down cartridges, it sacrifices a bit of bullet weight and cross sectional density to gain blistering speeds, albeit in this case, it does it rather superfluously to the point that it didn’t catch on in popularity, forcing Cor-Bon/Glaser LLC to stop manufacturing the rounds due to low demand.

Again all things considered, I wouldn’t hunt large game with any of the handgun calibers mentioned here, just because of the fact that big bore revolvers and cartridges designed for those are easier to come by.

Revolver calibers List

A note on this list as well.

Just as we didn’t include revolver rounds in the semi-auto handgun calibers list, we did the same here. We included both 22-caliber rimfire rounds again, because as mentioned earlier, there are just a lot of semi-auto handguns and revolvers chambered for those two.

While in general, revolvers can only accept rimmed cartridges, some revolvers have a cylinder recess for moon clips out of the box, and moon clips allow for rimless cartridges to be chambered in appropriate-caliber revolvers.

Some revolver enthusiasts have their revolver’s cylinder reamed by competent gunsmiths to allow for moon clips. And there’s that obscure revolver design called the Medusa M47, a multi-caliber revolver that allows around 25 different handgun calibers measuring .35 inches in diameter to be chambered in it.

Again, to make things simpler, we are not including any semi-auto handgun calibers in this list.

Revolver Calibers For Plinking

As with semi-auto plinking calibers, we only want to consider price when shopping around for revolver plinking rounds.

The .22 LR is still the undisputed king of plinking rounds at $0.09 a pop.

It doesn’t matter if you’re into semi-autos or revolvers, you really have to have a gun chambered in .22 LR if you want extended hours of plinking fun.

Revolver Calibers For Self Defense

I know what you’re thinking. Why is the .357 Magnum the cheapest on the list? 

Self Defense Revolver Calibers – Pricing

Well, it’s because of its popularity, due to the fact that it’s a proven manstopper and there are a huge lot of revolvers manufactured to chamber it.

The .38 Special standard pressure round will be cheaper but except for a very few misfits who carry old alloy revolvers, the majority of handgunners consider it pointless. I myself, being a revolver enthusiast, would feel kind of undergunned if I were to carry a .38 revolver loaded only with standard pressure  rounds, which is why I decided to only include its  +P variant in the list.

Round per round, the .38 Special +P isn’t that much more expensive compared to the .357 magnum, it’s only a $0.07 difference at most. What it has going for it is the fact that all .38 Special revolvers are lighter and relatively smaller compared to even the smallest revolvers in .357 like Ruger’s SP101, making them easier to carry concealed.

Self Defense Revolver Calibers — Muzzle Energy

Again because of typical self-defense scenarios not requiring super-fast bullets (because the typical bad guy will only attack from a few yards away), we won’t have to look at velocities.

The graph above shows that the .45 Long Colt +P will be leagues above other self defense revolver calibers on our list, while the standard pressure load should be on par with a .45 ACP. If you carry a Taurus Judge or a S&W Governor, you made a good choice.

I personally wouldn’t want a revolver in .45 Long Colt though. Yes, the +P loads are powerful, but they’re also the most expensive revolver cartridge on our list.

As a special mention, Ruger’s SP101 revolvers in .327 Federal Magnum holds six rounds while those chambered for .357 Magnum only holds five. These are some of the smallest all-steel magnum revolvers on the market. And the .327 Federal Magnum is no slouch, only around a hundred foot pounds less powerful than a hot .357 Magnum load.

Revolver Calibers For Varmint

As with varmint calibers for semi-auto handguns, the .22 LR is still the cheapest revolver round for hunting varmint. In fact it could very well be the cheapest of all calibers whether we’re talking semi-autos, revolvers or rifles. But let’s not belabor that point. Moving on…

Whereas with semi-auto handgun calibers, the only real contender for varmint is the .22 WMR, that is not the case with revolver calibers.

The .17 HMR bullet flying out of a revolver barrel at 2,350 feet per second is the fastest of all varmint calibers. It also happens to be the fastest bullet in our list bar none. And they’re also cheap at just $0.20 per round.

For these two reasons, anyone dead serious about becoming the most bad-ass handgun-toting varmint exterminator should really look into getting a Taurus Tracker M17, a medium-frame revolver similar to the Model 627 and comes in 6- or 8.5-inch heavy barrel.

Revolver Calibers For Medium Game

The revolver calibers below are the only three that I think will be great for hunting deer up to a hundred yards away.

Medium Game Revolver Calibers — Pricing

The graph below shows, again, that the venerable .357 Magnum being one of the cheapest revolver calibers on the market today is the go-to round for when you want to hunt deer and you don’t have a lot of buck to spend (pun not intended).

Medium Game Revolver Calibers — Ballistics

And looking at the ballistic performance graph below, the hottest .357 Magnum hunting loads are almost in the same energy category as the .41 Magnum, another magnum round that fills the gap between the .357 and the .44 magnums.

If you’ve never shot a long barrel magnum revolver before, you’re missing out on a lot.

We have a list of some of the best revolvers chambered for the .357 Magnum, you ought to check it out.

Revolver Calibers For Large Game

Majority (17) of the handgun calibers on our list are semi-auto rounds for self defense.

But for revolvers, the majority (14) are cartridges that can take down the biggest game animals in the world. Why is that?

Large Game Revolver Calibers — Pricing

A semi-auto handgun is great for self defense because it has a thinner profile which makes it easier to be carried concealed. But the thicker revolver frame can withstand more punishment from the most powerful cartridges.

While there are quite a number of people who have taken down up to elk- and bear-size game with .357 Magnum rounds hot-loaded to Elmer Keith specs, the consensus among handgun hunting enthusiasts is it’s only going to be barely adequate.

This is why I decided not to include the .357 Magnum in our list of large game revolver calibers. Instead, the bare minimum I would recommend for big game is the .357 Maximum, a more powerful version of the .357 Magnum. At $1.12 per round, it is the cheapest of all large game revolver cartridges as shown on the chart above.

Unfortunately, there aren’t a lot of revolvers on the market today that can shoot this potent round. Ruger has some Blackhawks and there are a few Dan Wesson revolvers floating around for sale on the interwebz.

If you don’t already happen to own one of these .357 Maximum revolvers, then you’ll have to move up in the caliber spectrum. For just $1.60 a pop, .44 Magnum rounds will be your minimum bet if you want a powerful handgun for grizzly bear.

The Taurus Raging Bull in .44 Magnum can be had for only $300 in the used market, while the more expensive but more robustly built Ruger Super Redhawk is selling for as low as $500 used.

If you don’t mind spending more, consider the S&W 629 Performance Center Stealth Hunter model. It’ll cost around ~$1,000 but you get what you pay for.

 Large Game Revolver Calibers — Ballistics 

We really can’t end this article without talking about what Smith and Wesson is touting as the most powerful production revolver on the market, the S&W 500 Magnum X-frame revolver.

Yes, it is THE most powerful production revolver which also makes it THE most powerful production handgun in the whole world, and Smith and Wesson wouldn’t make such a grand claim if their 50-caliber revolver chambers anything that isn’t the most powerful 50-caliber round on the market, the .500 S&W Magnum.

Focus on the gray bars on the chart below and you’ll see why.

Personally I think the .500 S&W Magnum is just too much power for even the largest game animals in the planet.

Other supposedly weaker 50-caliber wildcat rounds like the .500 Linebaugh, the .500 Wyoming Express and the .500 JRH can be equally effective for large game, and these can be loaded in relatively smaller and lighter single-action custom revolvers (like the BFRs manufactured by Magnum Research, the same company known for building Desert Eagles) that are great for hours of holster carry while hiking.

Granted, a smaller and lighter revolver will have significantly more recoil than a bigger and heavier one, but when you’re only a few meters away from a charging bear, recoil shouldn’t be an issue no matter how recoil shy you are because you’ll get high on adrenaline.

I personally don’t much prefer single action revolvers because their cylinders require extra care to unload before they can be reloaded with fresh cartridges, so if I were to pick a revolver in this category I would go for either a double action revolver in .44 Magnum (as I stated earlier) or a Smith and Wesson .460 XVR — if I really want the most power in a controllable package.

The XVR stands for “extreme velocity revolver” and uses the .460 S&W Magnum cartridge, its claim to fame being the fastest .45 caliber bullet on the market. Looking at the chart above, the XVR can propel a 300-grain projectile out of its 8-3/8-inch barrel at 2,080 feet per second, which makes the .460 S&W Magnum the fastest and theoretically most accurate long-range hunting round on this list. Because of its lighter bullets, recoil shouldn’t be as heavy as that of its bigger 50-caliber brother.


Recommendations

If you didn’t have time to read through the entirety of this article, here’s everything summarized:

  • For plinking, the .22 LR is just unrivaled when it comes to price per round, regardless of whether you prefer a semi-auto or a revolver.
  • For hunting varmint, nothing is faster than the .17 HMR, and it has about the same price per round as the .22 WMR. But it’s only for revolvers (and rifles). We wouldn’t recommend any semi-auto calibers for varmint.
  • For self defense, you can’t go wrong with any of the four most common semi-auto handgun calibers — .380 ACP, 9mm, .40 S&W and .45 ACP.
  • If you want the latest in semi-auto terminal ballistics development, look into the .22 TCM.
  • For revolvers, the best self defense round is the .357 Magnum, all things considered. But you might want to look into the .327 Federal Magnum, which performs almost similarly but is chambered in smaller revolvers.
  • For hunting medium game, the most sensible choices are the 10mm for semi-autos and again, the .357 Magnum for revolvers.
  • For hunting large game, the only option for semi-auto handgun cartridge is the .50 AE, but the Desert Eagle is real expensive. It makes more sense to just get a durable large frame revolver in .44 Magnum and load it with the hottest loads you can find if you’re hunting bear.
  • If you want more power for large game,  consider the .460 S&W Magnum. It’s the second most powerful revolver caliber on our list and shouldn’t recoil as bad as a .500 S&W Magnum.

Conclusion

There are a ton of handgun calibers available out there. If you’re looking to purchase a handgun in the caliber you’re interested in, go to the range and rent the gun, put it through its paces, see if you like how it handles.

Also, do your homework on the caliber’s ballistic performance, launching platform and ammo availability. Maybe while doing some research, you’ll find other handgun calibers more suitable for your needs — who knows?

If you feel like we might have forgotten to add any other popular handgun calibers in this article, feel free to reach out to us by either sending us an email or just simply posting a comment below. We’ll be more than happy to include them on our list.

A firearms and ballistics enthusiast and an outdoorsman, Mike is one of Gun News Daily's best contributing authors. He's a researcher, data analyst and writer by trade and strongly adheres to conservatism—a stalwart of the right to keep and bear arms.